Network dysconnectivity underlies depression in premanifest Huntington disease gene-expansion carriers
Abstract
This thesis examines the structural and functional brain networks involved in depression for people with premanifest Huntington's disease (HD). It identifies that depression is related to changes in communication of depression- and HD-related hub regions and functional networks, but not atrophy of these regions.
Fields of Study & Subjects
Functional Brain Connectivity Studies
Genetic Neurodegenerative Diseases
Neurological disorders and treatments
Publication details
- Journal / source
- Monash University
- Publication date
- 1 January 2026
- Document type
- Thesis