The development and evaluation of DNA vaccines against whooping cough using a murine respiratory model of infection
Abstract
In this study, a suite of single antigen DNA vaccines, combination DNA vaccines and dual modality vaccines, were developed and evaluated for their potential to induce humoral and cell-mediated immune responses, and protective efficacy against Bordetella pertussis, the aetiological agent of whooping cough, using the mouse respiratory challenge model.
Fields of Study & Subjects
Bacterial Infections and Vaccines
Influenza Virus Research Studies
Pneumonia and Respiratory Infections
Publication details
- Publication date
- 31 July 2026
- Language
- EN
- Document type
- Thesis