Beyond traditional ligands: chelating peptoids as polydentate macrocyclic ligands for luminescent Eu-based biolabels

ChemRxiv 2026 Preprint Open access

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Authors: Alena S. Kalyakina, Anne C. Schneider, Anna Meschkov, Olaf Fuhr, Ute Schepers, Stefan Braese
DOI: 10.26434/chemrxiv-2026-pbcnj
Cited by: 0

Abstract

We report the synthesis and characterization of a series of Eu-labeled cyclic peptoids and evaluate their potential as luminescent probes for biological applications. Our results suggest that Eu-peptoid hybrids represent a promising class of luminescent probes for bioimaging, with potential applications in disease diagnosis, drug discovery, and fundamental biological research.

Fields of Study & Subjects

Lanthanide and Transition Metal Complexes Chemical Synthesis and Analysis Radiopharmaceutical Chemistry and Applications

Publication details

Journal / source
ChemRxiv
Publication date
6 January 2026
Document type
Preprint