Boron Heterocycles via Direct Activation of Nitriles & Carbodiimides by alpha-Heteroboronates

ChemRxiv 2026 Preprint Open access

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Authors: Richard J. Procter, Usman Shabbir, Liudmila Akopova, Matthew Cross, Helen Allan, Carl J. Mallia, Robert P. Law, Dejan‐Krešimir Bučar, Michael J. Porter, Matthew W. Powner, Tom D. Sheppard
DOI: 10.26434/chemrxiv-2026-x44db
Cited by: 0

Abstract

Boron heterocycles can be formed at ambient temperature through the reaction of alpha-thio or alpha-amino boronates with nitriles or carbodiiimides. The chemistry can be applied to a wide range of unactivated nitriles. A range of amino acid and peptide analogues containing novel boron heterocycles were generated using these reactions.

Fields of Study & Subjects

Organoboron and organosilicon chemistry Click Chemistry and Applications Boron Compounds in Chemistry

Publication details

Journal / source
ChemRxiv
Publication date
13 January 2026
Document type
Preprint