Azide-to-Diazo-Facilitated Michael Addition via Phosphazide Formation
Abstract
A new type of Michael addition based on azide-to-diazo conversion is disclosed. This unusual transformation proceeds via 1,4-addition accompanied by N-N bond cleavage of phosphazide intermediates under practical conditions. The high versatility of the resulting Michael adducts enables the synthesis of a wide variety of organonitrogen compounds.
Fields of Study & Subjects
Cyclopropane Reaction Mechanisms
Phosphorus compounds and reactions
Organic Chemistry Cycloaddition Reactions
Publication details
- Journal / source
- ChemRxiv
- Publication date
- 3 February 2026
- Document type
- Preprint