Digital infrastructure to support daily high-throughput experimental materials research
Abstract
High-throughput and autonomous experimentation generate complex, heterogeneous datasets whose reuse, large-scale analysis, and linking to data from first-principles calculations remain challenging. Here, we report on an operational deployment of the open-source NOMAD Oasis data infrastructure as a digital backbone for daily high-throughput experimental work in a materials discovery group at DTU Nanolab. The customized platform supports the complete experimental workflow in a thin-film laboratory, linking physical inventory items, automated synthesis logs, high-throughput characterization data, and cloud-based analysis within a unified data model. The platform preserves full sample provenance across multi-step workflows and uses unified sample coordinates to enable direct cross-technique correlation. We demonstrate the capabilities of the platform on a combined experimental-computational project centered on phosphosulfide thin-film libraries. The data consists of 12,000 experimental samples acquired during routine operation over 18 months, complemented by more than 800 first-principles calculations - all managed in a unified data platform. We show how an open, extensible data infrastructure system supports reproducible workflows, scalable analysis, and long-term data reuse.
Fields of Study & Subjects
Machine Learning in Materials Science
Scientific Computing and Data Management
Catalysis and Oxidation Reactions
Publication details
- Journal / source
- ChemRxiv
- Publisher
- American Chemical Society (ACS)
- Publication date
- 16 February 2026
- Document type
- Preprint