Leveraging Mechanism-Based Inhibition to Enable the Engineering of Enzymatic Activity towards Polyurethane

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Authors: Luís M C Teixeira, Pedro Paiva, Laura Rotilio, Jens Preben Morth, Pedro Alexandrino Fernandes, Maria João Ramos
Cited by: 2

Abstract

Polyurethane (PU) is widely used due to its low-cost production, stability and structural versatility. However, due to inadequate waste management, the widespread use of this material has raised environmental concerns. Recently, academic and industrial efforts have been made to discover enzymes capable of depolymerizing PU. Nevertheless, the enzymes discovered to date lack sufficient efficiency and stability for industrial implementation, requiring further engineering. In

Fields of Study & Subjects

biodegradable polymer synthesis and properties Polymer composites and self-healing Microplastics and Plastic Pollution

Publication details

Journal / source
ChemRxiv
Publisher
American Chemical Society (ACS)
Publication date
19 February 2026
Document type
Preprint