Facile Approach to Geminal Bisperoxides via BR3/O2-Enabled Peroxidation of Aldehydes

ChemRxiv 2026 Preprint Open access

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Authors: Terim Seo, Gyoungho Noh, Do Hyun Ryu
DOI: 10.26434/chemrxiv.15004735/v1
Cited by: 1

Abstract

A trialkylborane/O 2 -enabled peroxidation of aldehydes for the selective synthesis of geminal bisperoxides is reported. A range of geminal bisperoxides was obtained in high yields (up to >99%) from simple precursors. The synthetic utility was demonstrated through their diverse transformations into azidoperoxides, cyanoperoxides, peroxyesters, esters, and carboxylic acids. Mechanistic studies support the involvement of a radical pathway.

Fields of Study & Subjects

Oxidative Organic Chemistry Reactions Radical Photochemical Reactions Catalytic C–H Functionalization Methods

Publication details

Journal / source
ChemRxiv
Publisher
American Chemical Society (ACS)
Publication date
15 June 2026
Document type
Preprint