A clinical case of erythromelalgia in a patient comorbid with antiphospholipid syndrome

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Authors: Anna A. Kudrjavtseva, A. V. Meladze, Ekaterina Trapeznikova, Левшина Анна Романовна, Dmitry A. Napalkov, Anastasiya A. Sokolova
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References: 42

Abstract

The article presents a clinical case of secondary erythromelalgia in a comorbid patient with antiphospholipid syndrome, accompanied by burning pain, hyperemia and swelling of the lower extremities. A comprehensive examination involving a neurologist, dermatologist, and rheumatologist was conducted to establish the diagnosis and select the optimal therapy. Significant clinical improvement in the patient's condition is demonstrated against the background of pregabalin therapy. The importance of a multidisciplinary approach and the difficulty of diagnosis due to the lack of specific examination methods and insufficient awareness of doctors about this disease are emphasized. The described case demonstrates the need for a personalized approach to managing patients with erythromelalgia to improve their quality of life.

Fields of Study & Subjects

Pain Management and Treatment Pain Mechanisms and Treatments Systemic Lupus Erythematosus Research

Publication details

Journal / source
Terapevticheskii arkhiv
Volume
97
Issue
12
Pages
1018–1022
Publication date
14 February 2026
Language
RU