Probiotics’ position in clinical practice: focus on the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12). A review

Terapevticheskii arkhiv 2026 Open access

Read full text
Authors: Горелов Александр Васильевич, Roman Sergeevich Kozlov, Irina V. Andreeva, Арова Анна Анатольевна, И.А. Бавыкина, Marina S. Grigorovich, E V Dovgan, Константин Дмитриевич Ермоленко, Olga V. Zaytseva, Sergey M. Zakharenko, В. В. Зеленская, Sergey Kensarinovich Zyryanov
+16 more Natalya A. Ilyenkova, M. A. Kachkovsky, Tatiana A. Kogut, Elena G. Kondyurina, Krasnov VP, Evelina E. Lokshina, V. F. Privorotskiy, Marina N. Repetskaya, Marina F. Rzyankina, С. Н. Серикова, Оlga U. Stetsiouk, Denis V. Usenko, L. V. Khanipova, Александр МихайЛович Шабалов, Mikhail A. Shevyakov, L. V. Yakovleva
DOI: 10.26442/00403660.2025.12.203481
Cited by: 0
References: 27

Abstract

Probiotics are currently widely used in clinical practice to prevent and treat a wide range of diseases. The purpose of our review is to highlight what we consider to be the most significant clinical studies on the use of probiotics for preventing antibiotic-associated diarrhea, clostridial diarrhea and pseudomembranous colitis. The article also presents the results of studies confirming the efficacy of probiotics in Helicobacter pylori eradication therapy. The review focuses on Linex® Forte, medicinal product containing the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12).

Fields of Study & Subjects

Probiotics and Fermented Foods Infant Nutrition and Health Gastrointestinal motility and disorders

Publication details

Journal / source
Terapevticheskii arkhiv
Volume
97
Issue
12
Pages
1037–1043
Publication date
14 February 2026
Language
RU