Research on the Efficacy of Autologous Periosteum Graft Combined with PRP in the Treatment of Long Bone Fractures in the Extremities

Objective: To analyze the clinical application value of autologous periosteum graft combined with platelet-rich plasma (PRP) in the treatment of long bone fractures in the extremities. Methods: A total of 40 patients with long bone fractures in the extremities admitted to Santai Hospital Affiliated to North Sichuan Medical College from January 2023 to January 2025 were included, including cases of upper extremity forearm fractures and lower extremity femoral and tibial fractures. The patients were evenly divided using a random number table, with the control group undergoing open reduction and internal fixation (ORIF) combined with autologous periosteum graft, and the observation group undergoing ORIF, autologous periosteum graft, and PRP injection. Surgical indicators, complication rates, excellent fracture healing rates, functional satisfaction, and joint range of motion were compared between the two groups. Results: The surgical indicators in the observation group were similar to those in the control group (p > 0.05). The complication rate in the observation group was lower than that in the control group, while the excellent fracture healing rate and functional satisfaction were higher in the observation group (p < 0.05). Conclusion: Autologous periosteum graft combined with PRP technology is safe and reliable for the treatment of long bone fractures in the extremities, with satisfactory clinical outcomes.