Neutrophil-Lymphocyte Ratio and Platelet Recovery Time as Prognostic Markers in Paediatric Dengue: A Prospective Observational Study
Abstract
Background: Dengue fever remains a significant public health challenge in tropical regions, with paediatric populations being particularly vulnerable to severe manifestations. Early identification of prognostic markers is crucial for timely intervention and improved clinical outcomes. This study aimed to evaluate the utility of neutrophil-lymphocyte ratio (NLR) and platelet recovery time as prognostic markers in paediatric dengue patients. Methods: A prospective observational study was conducted among 25 paediatric patients (aged 1-14 years) diagnosed with dengue fever at a tertiary care hospital over six months. Serial measurements of complete blood counts were performed, and NLR was calculated at admission and during the course of illness. Platelet recovery time was documented, and correlations with disease severity were analysed. Results: The mean age of participants was 8.2 ± 3.4 years, with male predominance (56%). Patients with severe dengue demonstrated significantly higher NLR values (4.82 ± 1.24) compared to non-severe cases (2.14 ± 0.68; p
Fields of Study & Subjects
Mosquito-borne diseases and control
Inflammatory Biomarkers in Disease Prognosis
Sepsis Diagnosis and Treatment
Publication details
- Journal / source
- Medico Research Chronicles
- Volume
- 12
- Issue
- 6
- Pages
- 550–560
- Publication date
- 5 February 2026
- Language
- EN