High prevalence of tetracycline resistance in Neisseria gonorrhoeae across 22 European countries, 2024

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Authors: Susanne Jacobsson, Michelle J Cole, Melissa Jansen van Rensburg, Daniel Schröder, Otilia Mårdh, Csaba Ködmön, M Unemo, the Euro-GASP tetracycline study group
Cited by: 2
References: 15

Abstract

In 2024, based on the European Committee on Antimicrobial Susceptibility Testing breakpoint, we observed a tetracycline resistance prevalence of 62.3% (2,231/3,579) in Neisseria gonorrhoeae isolates from 22 European countries (range: 16.5–100%). Multivariable analysis of correlations between resistance and patients’ epidemiological characteristics found tetracycline resistance associated with men who have sex with men (aOR: 1.38; 95% CI: 1.06–1.79). Our results are important when considering measures against transmission of sexually transmitted bacterial infections in Europe, such as in the context of doxycycline post-exposure prophylaxis (doxy-PEP).

Fields of Study & Subjects

Reproductive tract infections research Bacterial Infections and Vaccines Neonatal and Maternal Infections

Publication details

Journal / source
Eurosurveillance
Publisher
European Centre for Disease Control and Prevention (ECDC)
Volume
31
Issue
2
Publication date
15 January 2026
Language
EN