Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026

Eurosurveillance 2026 Open access

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Authors: Allan De Clercq, François Blanquart, Vincent Vieillefond, Benoît Visseaux, Alexandra Jacques, Stéphanie Haïm‐Boukobza, Valentin Wehrle, Guillaume Deleglise, Thomas Duret, Sibylle Bernard-Stoecklin, Danielle Perez-Bercoff, Antoine Oblette
+6 more Lina Bruno, Marie Anne Rameix-Welti, Laurence Josset, Vincent Enouf, Antonin Bal, on behalf of the RELAB study group
DOI: 10.2807/1560-7917.es.2026.31.2.2500992
Cited by: 12
References: 14

Abstract

In Europe, the 2025/26 seasonal influenza epidemic started in October 2025. Co-circulation of A(H3N2) and A(H1N1)pdm09 was observed in several countries including France. We estimated early vaccine effectiveness (VE) against influenza virus in French outpatients (5,451 positives/18,816 negatives). A significant VE across all age groups was measured: 28% (95% CI: 17-37) for those aged ≥ 65 years, 45% (95% CI: 36-53) for 18-64-year-olds and 57% (95% CIs: 29-74) for 0-17-year-olds. Reinforcing vaccination uptake is warranted.

Fields of Study & Subjects

Influenza Virus Research Studies Respiratory viral infections research Immune responses and vaccinations

Publication details

Journal / source
Eurosurveillance
Publisher
European Centre for Disease Control and Prevention (ECDC)
Volume
31
Issue
2
Publication date
15 January 2026
Language
EN