First detection and autochthonous transmission of monkeypox virus clade Ib in the Netherlands, October to November, 2025

Eurosurveillance 2026 Open access

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Authors: Jelte Elsinga, Celine A. van de Ven, Anne de Vries, Hester Coppoolse, Mariska Petrignani, Brigitte van Cleef, Riemer van Markus, Nora C. Carpay, Catharina E van Ewijk, Sjoerd Rebers, Aldert Bart, Karin von Eije
+12 more Brenda M. Westerhuis, Sylvia Bruisten, Leonard Schuele, Marjan Boter, Richard Molenkamp, Bregtje A. Lemkes, Suzanne E. Geerlings, Henry JC de Vries, Marion Koopmans, Marcel Jonges, Bas B. Oude Munnink, Matthijs R. A. Welkers
DOI: 10.2807/1560-7917.es.2026.31.3.2500958
Cited by: 1
References: 4

Abstract

In October-November 2025, eight autochthonous cases of monkeypox (MPXV) clade Ib virus infection were reported in the Netherlands. All cases were men who have sex with men aged 25-65; none required hospital admission or antiviral treatment. Phylogenetic analysis combined with contact tracing suggest multiple introductions or cryptic circulation with onwards transmission within the community. Highly related international sequences were identified dating back to August 2025, indicating sustained global community transmission of clade Ib outside the African continent.

Fields of Study & Subjects

Poxvirus research and outbreaks Viral Infections and Outbreaks Research HIV Research and Treatment

Publication details

Journal / source
Eurosurveillance
Publisher
European Centre for Disease Control and Prevention (ECDC)
Volume
31
Issue
3
Publication date
22 January 2026
Language
EN