The relationship between prior cinacalcet therapy and the course of hungry bone syndrome in patients who underwent surgery for secondary hyperparathyroidism

Nephrology and Dialysis 2026 Open access

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Authors: E. V. Parshina, A. D. Tolkach, K. Yu. Novokshonov, R. A. Chernikov, A.Y. Zemchenkov
DOI: 10.28996/2618-9801-2026-1-61-72
Cited by: 1
References: 21

Abstract

Introduction . Hypocalcaemia, including hungry bone syndrome (HBS) after parathyroidectomy (PTE), is associated with adverse outcomes, yet its prevention is often inadequate. We evaluated whether preoperative cinacalcet therapy reduces the risk severe postoperative hypocalcemia. Methods . A retrospective, single-center study (2011-2019) included 713 patients. The primary endpoint was of hypocalcemia, defined as an ionized calcium (Ca 2+ ) level below 0.9 mmol/L on day 2 or 3 after PTE. Secondary endpoints included the need for intravenous calcium supplementation and length of hospital stay (

Fields of Study & Subjects

Parathyroid Disorders and Treatments Thyroid and Parathyroid Surgery Vitamin D Research Studies

Publication details

Journal / source
Nephrology and Dialysis
Publisher
Russian Dialysis Society
Volume
28
Issue
1
Pages
61–72
Publication date
1 April 2026