Bioethics in the Use of Laboratory Animals, Strategies for Reduction, Replacement, and Refinement in rodents

This literature review addresses the use of animals in scientific research from a bioethical perspective, focusing on the principle of the "3Rs" (Replacement, Reduction, and Refinement). Through a literature search, the strategies needed to reduce the number of animals used, replace them with alternative models, in a search for experimental techniques that minimize their suffering were analyzed. The goal is to promote more ethical and sustainable research, balancing scientific benefits with animal welfare. This review emphasizes the need to adopt innovative and collaborative practices, contributing to science that prioritizes both progress and respect for animal life.