Investigations on the Immunomodulatory Effects of Streptomyces and Bacillus-Based Probiotics in Broilers

This study was planned to evaluate the immunomodulatory potential of Streptomyces and Bacillus-based probiotic formulations in broiler chickens.Dayold (n=90) broiler chicks were randomly allocated to six experimental groups (n=15 each), including: Group A served as a negative control; Group B was administered with Streptomyces sp.@ 1×10 9 CFU/kg; Group C was administered with Bacillus sp.@ 1×10 8 CFU/kg; Group D was administered a commercial probiotic (Probio TM ) @ 2g/kg; Group E was administered with Streptomyces sp. and Bacillus sp.@ 1×10 9 CFU and 1×10 8 CFU/kg, respectively, and Group F was administered with Streptomyces sp., Bacillus sp. and E. coli Challenge @ 1×10 9 CFU/kg, 1×10 8 CFU/kg and 3×10 7 CFU/mL of broth culture, respectively.The treatments were given in feed from day seven till the Day 42 of age.The results indicated more pronounced immunostimulatory effects in the Streptomyces-Bacillus combination (Group E) those were evident by significant increase (P