Relationship Between the Atherogenic Index of Plasma and Glycated HbA1C, Serum Uric Acid, and Homocysteine in Type 2 Diabetes and Acute Stroke

OBJECTIVE: To examine the association between the atherogenic index of plasma (AIP) and glycated haemoglobin A1c (HbA1c), serum uric acid (SUA), and homocysteine (Hcy) in individuals with type II diabetes mellitus (T2DM) and acute stroke. STUDY DESIGN: A descriptive study. Place and Duration of the Study: Department of Endocrinology, First Central Hospital of Baoding, Hebei, China, from January 2023 to January 2024. METHODOLOGY: Ninety patients were categorised based on NIHSS score: mild (n = 30), intermediate (n = 30), and severe (n = 30). Forty healthy participants were selected as the comparison cohort. Variations in lipid profiles, blood glucose, SUA, and Hcy concentrations were compared. Logistic regression analysis was conducted to determine the risk factors for T2DM and acute stroke. Spearman's rank correlation assessment was used to evaluate the relationship between AIP and HbA1c, SUA, and Hcy. RESULTS: The comparison cohort demonstrated a lower frequency of hypertension compared to the mild (χ2 = 4.667; p = 0.031), moderate (χ2 = 8.750; p = 0.003), and severe cohorts (χ2 = 12.153; p