Chilblain Lupus Erythematosus in an Adult Female: A Case Report

Background: Chilblain Lupus Erythematosus (CHLE) is a rare, chronic subtype of Cutaneous Lupus Erythematosus (CLE), typically affecting acral sites during cold weather. Its clinical and histopathological overlap with other conditions often leads to misdiagnosis.Case presentation: We report a case of a 35-year-old Middle Eastern female from Syria, who presented with recurrent erythematous lesions on the face and acral areas exacerbated during winter. Initial diagnosis suggested Discoid Lupus Erythematous (DLE) based on skin biopsy. Further clinical evaluation and laboratory investigation confirmed CHLE. The patient responded remarkably to topical corticosteroids and cold protection measures.Conclusion: This condition should be considered in patients with recurrent acral lesions triggered by cold exposure. This case underscores the importance of distinguishing CHLE from perniosis and other CLE subtypes through thorough clinical and histopathological assessment.