Optimization of Therapy in Patients with Paranoid Schizophrenia and Non-suicidal Autoaggression who have recovered from Coronavirus Infection

The issue of comorbidity of coronavirus infection and chronic mental disorders remains an important medical problem, determining the relevance of the study. A continuous, non-randomized method was used to conduct a comparative analysis of combination therapy in 124 patients with paranoid schizophrenia with non-suicidal autoaggressive behavior (abbreviated NAAB) who have had coronavirus infection. A clinical method and experimental psychometric research methods were used, including brief psychiatric assessment scales; social functioning scales and a visual analog pain scale. The clinical picture features during the period of remote consequences of the transferred coronavirus infection in the examined persons were established. It was established that antipsychotics in combination with non-steroidal anti-inflammatory drugs have a positive clinical effect in the examined persons.Moreover, additional administration of drugs with osmotic dehydrating activity statistically significantly increases the clinical effect of the treatment in relation to the leading psychopathological features, including NSAB in this group of patients.