A Case Study on Post‑Transplant Diabetes Mellitus Following Renal Transplantation

Post‑transplant diabetes mellitus (PTDM), previously referred to as new‑onset diabetes after transplantation (NODAT), is a common metabolic complication following solid organ transplantation. It is associated with increased cardiovascular morbidity, infection risk, graft dysfunction, and mortality. The development of PTDM is multifactorial, involving pre‑existing patient risk factors and the diabetogenic effects of immunosuppressive therapy. This case study describes a 38‑year‑old male renal transplant recipient who developed PTDM in the early post‑transplant period. The patient had a background of end‑stage renal disease managed with haemodialysis prior to receiving a living donor renal transplant. Post‑transplant, he experienced recurrent infections, graft dysfunction, and persistent hyperglycaemia, leading to the diagnosis of PTDM. This report highlights the clinical course, risk factors, diagnostic considerations, and management strategies, with emphasis on the nursing role in early detection, patient education, and long‑term follow‑up. Early recognition and appropriate management of PTDM are essential to improve patient and graft outcomes.