The review on versatile study of Alzheimer’s Disease (AD) and their etiology, pathophysiology, common mechanism of action of drugs used in current treatment

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Authors: Aruna J., Lokesh A., G. Madhavan V. Dhanalakshmi, R. Guhan, Kaviya S., Sanjay A., Saranyadevi P., Surekha P.
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Abstract

Alzheimer’s complaint (announcement) is the most common habitual neurodegenerative complaint worldwide and a leading cause of madness. It results in cognitive impairments similar as aphasia and agnosia, along with behavioral and cerebral symptoms that place a significant emotional and fiscal burden on cases and their families. First described by Alois Alzheimer in 1907, announcement is classified into domestic and sporadic forms. presently, over 47 million people are affected encyclopedically, with figures anticipated to rise sprucely by 2050. The complaint is characterized by amyloid pillars and neurofibrillary befuddlements formed by amyloid- β and tau proteins. Announcement is multifactorial, with the cholinergic and amyloid suppositions being central to its pathogenesis. This review summarizes recent advances in announcement mechanisms, memory impairment, opinion, treatment strategies, and ongoing clinical exploration.

Fields of Study & Subjects

Alzheimer's disease research and treatments Dementia and Cognitive Impairment Research Cholinesterase and Neurodegenerative Diseases

Publication details

Journal / source
World Journal of Advanced Research and Reviews
Volume
29
Issue
2
Pages
631–644
Publication date
13 February 2026
Language
EN