Analysis of the renin-angiotensin-aldosterone system in men with hypertension and atrial fibrillation

A group of men with hypertension (HT) was examined. The patients were divided into three groups: those with paroxysmal atrial fibrillation (AF), those with persistent AF, and those with coronary artery disease (CAD) (2–3 FC angina).When analyzing the parameters of the renin-angiotensin-aldosterone system, it was revealed that patients with GB and AF are more likely to have high–grade arterial hypertension (AH) (up to 50%), and in patients with GB and CHD — normorenin hypertension (60%). Among patients with high-RH hypertension, significantly higher renin values were noted in the group with persistent AF and coronary artery disease. Against the background of taking antihypertensive therapy (b-blockers and BAR), the level of aldosterone was within the normal range in all examined patients. The high level of angiotensin II in the group of persons with high-renin AH and AF requires further study. Hypokalemia was detected only in patients with hypertension and paroxysmal AF in 13.4% of cases. It should be noted that a low level of K + from 3.5 to 3.9 mmol/L was detected in 34.2% of patients with paroxysmal AF and in 30% of patients with persistent AF. No correlation was found between the renin-angiotensin-aldosterone system and the K + level.