Neurosarcoidosis
Abstract
Neurosarcoidosis is a rare manifestation of systemic sarcoidosis characterized by involvement of both the central and peripheral nervous systems. The clinical presentation is highly variable and depends on the localization of granulomatous inflammation, which complicates the diagnostic process. This article reviews current understanding of the pathogenesis, clinical phenotypes, and differential diagnosis of neurosarcoidosis. It also describes methods of neuroimaging, laboratory diagnostics, and histological verification of the disease. Special attention is given to therapeutic strategies, including glucocorticoid and immunosuppressive therapy. Prognostic considerations and potential directions for future research are discussed.
Fields of Study & Subjects
Sarcoidosis and Beryllium Toxicity Research
Histiocytic Disorders and Treatments
Vasculitis and related conditions
Publication details
- Journal / source
- Clinical Medicine (Russian Journal)
- Volume
- 103
- Issue
- 12
- Pages
- 865–872
- Publication date
- 3 March 2026
- Language
- EN