Efficiency of a drug based on ivermectin and praziquantel against parasitic diseases in cattle

The purpose of the research is to evaluate the therapeutic efficacy and safety of a combined antiparasitic drug containing ivermectin and praziquantel against various forms of parasitic diseases in cattle. Materials and methods . The study was conducted on a farm in the Kaliningrad Region from July 29 to October 14, 2024. Of 890 animals, 50 heifers in the age of 8–14 months diagnosed with nematodosis, cestodosis, trematodosis, arachnoid infections, and myiasis were selected for the experiment. The animals were divided into five groups according to the type of infection. The drug was administered orally with feed or a milk replacer at doses appropriate for the body weight and the type of disease. Diagnostic procedures included clinical examination, coprological studies (Fülleborn, Shcherbovich), larvoscopy, microscopic examination of skin scrapings, and visual assessment. Results and discussion . Previously used methods demonstrated complete elimination of nematodosis and cestodosis with two applied doses of the drug; the efficacy against arachnoid infections and myiasis was 80–90%. The drug did not cause any side effects. Thus, the combined product which combines ivermectin and praziquantel is effective and safe for veterinary use and can be used for the treatment and prevention of multiple parasitic infections in cattle.