Efficacy and Safety of Blend of Beetroot and Pomegranate Extract on Strength, Endurance, Nitric Oxide Bioavailability and Body Composition: A Randomized, DoubleBlind, Placebo-Controlled, Cross-Over Trial in Healthy Active Males

Both nitrate and polyphenol pathways are known to support vascular function, muscle oxygenation, and endurance.A novel blend of Beetroot and Pomegranate Peel Extract (BPE) standardized for nitrates and ellagic acid content.This randomized, double-blind, placebo-controlled, two-period cross-over study evaluated the acute and 28-day effects of BPE in 18 healthy, physically active men on Nitric Oxide (NO) bioavailability, exercise performance, endurance and recovery.Participants received BPE (400mg/ day) or placebo for 28 days with a 14-day washout.Compared with placebo, BPE produced significant improvements in bench press one-repetition maximum (Day 28: 9.44±8.73kgvs 2.22±8.09kg;p=0.0146), leg press one-repetition maximum (13.06±9.10kgvs 4.72±9.15kg;p=0.0097), dominant hand grip strength (3.28±2.88kgvs 1.01±1.98kg;p=0.0094), and six-minute walk distance (41.11±17.45mvs 12.22±17.68m;p