A PHARMACEUTICO-ANALYTICAL CHARACTERIZATION OF ARSENO-MERCURIAL FORMULATION: SAMEERAPANNAGA RASA

Background: Rasa Aushadhi's are known to play an important role in therapeutics due to their nanoparticle characteristics.A systematic study of the manufacturing processes for these formulations is essential to ensure their quality, safety, and efficacy, thereby preserving the deep trust patients have in Ayurveda.Aim & objectives: The present study aimed to prepare SPR as per the methods mentioned in the classical text and to characterize it physio-chemically using available analytical techniques.Materials & Methods: All the raw drugs were subjected to shodhana as per classical SOP and the final product was prepared by classical kupipakwa method by giving bhavana with Tulasi swarasa for three days.The qualitative and quantitative estimations were done for raw drugs, intermediate and final product.The characterization was done through XRD, SEM, FTIR, and ICP-AES Analysis.Results and Discussion: During the Sameera Pannaga Rasa preparation it was found that the time duration of Madhyama agni was longest i.e. 14 hrs which might be due the chemical reaction between organic and inorganic materials and obtaining the stable form.The maximum temperature