Barrett’s esophagus and comorbid pathology

Introduction. According to the literature data, in most of the conducted clinical studies, the authors include patients with a separate pathology, making comorbidity a criterion of exclusion. In our practice, we consider comorbidity as a criterion of clarifying diagnosis and determining treatment and terms of dynamic observation for patients with Barrett’s esophagus. The purpose of the work: presentation of the case of a patient with Barrett’s esophagus in conditions of comorbid pathology. Materials and methods. A patient with a comorbid pathology, including prostate cancer, pre-cancerous skin pathology, and psoriasis, was examined and treated. In order to implement a personalized approach, clinical, endoscopic, and morphological data were analyzed, as well as the results of immunohistochemical examination of biopsy material. As a result, the trans-syndromic nature of the comorbid pathology was confirmed, treatment was performed, and the duration of dynamic monitoring was determined. Conclusion. It has been proven that the pathological processes identified in the patient are components of a single trans-syndromic comorbid pathology - the syndrome of uncontrolled proliferation, which results in neoplastic changes, including those in the esophageal mucosa.