Eosinophilic gastritis in a child with a rare genetic pathology

Eosinophilic gastritis (EoG) is a form of eosinophilic gastrointestinal diseases (EGID), which has been increasing in the last decade, including in children. EoG is characterized by nonspecific symptoms of upper gastrointestinal tract lesions and eosinophilic infiltration of the gastric wall. Since EoG is a rare disease, uniform standards for diagnosis, differential diagnosis, treatment, and follow-up have not yet been developed. This article presents data on the prevalence, pathogenesis, and main clinical, endoscopic, and histological manifestations of Eo G. A clinical case of severe EoG in a child with a rare genetic disorder, Noonan-like syndrome, is presented. No association between eosinophilic gastrointestinal lesions and any gastrointestinal abnormalities in this syndrome has previously been described.