Malformaciones del desarrollo cortical, lo que usted debe saber

Introduction: Malformations of cortical development are a group of disorders that, although different from each other, share a focal or extensive development disruption of the cerebral cortex. This phenomenon has a clinical radiological translation, observing epilepsy and/or neurodevelopment disruption, as well as abnormal brain MRI findings in patients. Objectives: to make the reader aware that these disorders may seem to belong only to the neuroradiology or neuro-pediatrics fields, but they constitute a spectrum of diseases that should be recognized not only by pediatricians and radiologists, but also by general practitioners and other specialists, since they are a major cause of seizures and disrupted neurodevelopment. Methods: a case series of malformations of cortical development, is presented, selecting the most representative cases reviewed in the radiology service of Hospital Internacional de Colombia, during the period between 2021 and 2023. A literature review was conducted through the PubMed and Scopus databases using search words: malformations of cortical development and MRI. Discussion and conclusions: Malformations of cortical development are a heterogeneous group of disorders affecting cerebral cortical development in various manners and stages of neuronal formation, sharing common points and having a series of characteristics that generally present with anatomical alterations detectable in magnetic resonance imaging. This case series, with a literature review, presents the most common malformations in our setting, describing relevant radiological findings and key points of each one of them.