The Radical Prostatectomy Versus Brachytherapy for the Management of Low- and Intermediate-Risk Prostate Cancer: A Meta-Analysis of Observational Studies Focusing on Oncological Outcomes

Asian Pacific Journal of Cancer Prevention 2026 Open access

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Authors: Syah Warli, Muhammad Fahmi Ikram, Dhirajaya Kadar, Ginanda Siregar, Fauriski Febrian Prapiska, Lidya Imelda Laksmi, Zaimah Zulkarnaini Tala, Dewi IS Siregar, Mutiara Hartati Siregar
DOI: 10.31557/apjcp.2026.27.1.233
Cited by: 1

Abstract

OBJECTIVE: This study aims to compare the oncological outcomes of radical prostatectomy (RP) and brachytherapy (BT) in patients with low- and intermediate-risk prostate cancer, and determine whether one treatment demonstrates superiority over the other. METHODS: A systematic literature search was conducted using databases, including PubMed, ScienceDirect, Google Scholar, EBSCO, and the Cochrane Library, to identify relevant clinical studies. Hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted, with HRs >1 indicating RP superiority and HRs

Fields of Study & Subjects

Prostate Cancer Diagnosis and Treatment Prostate Cancer Treatment and Research Cancer Lipids and Metabolism

Publication details

Journal / source
Asian Pacific Journal of Cancer Prevention
Publisher
EpiSmart Science Vector Ltd
Volume
27
Issue
1
Pages
233–248
Publication date
1 January 2026
Language
EN