The Impact of Mood Disorders on the Rehabilitation Process in a Patient Diagnosed with CADASIL

ABS TRACT Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral small vessel disease that can cause different clinical symptoms such as recurrent ischemic attacks, migraine, epileptic seizures, and dementia.In this case report, a 45-year-old female patient was diagnosed with CADASIL disease after having recurrent ischemic cerebrovascular events a year apart, after genetic evaluation performed by neurology revealed a mutation in the gene encoding the NOTCH receptor.The patient was admitted to our clinic for rehabilitation, and sudden mood changes led to disruptions in the rehabilitation program.The patient was referred to a psychiatrist, and it was concluded that the mood disorders were attributed to CADASIL disease.In this case, we reported the effects of mood changes in CADASIL on the rehabilitation program and the positive impacts of the treatment of mood changes on the clinical process.We wanted to emphasize the importance of psychiatric disorders that may accompany CADASIL patients in the rehabilitation process.