The ratio of TG/CysC is a significant indicator of nephritis in children with IgA vasculitis
Abstract
The incidence of IgA vasculitis (IgAV) in children is relatively high. Cases with severe kidney involvement can lead to death. This study aimed to assess whether the ratio of triglyceride and cystatin C (TG/CysC) represented a risk factor for nephritis in children with IgAV. A total of 451 children were recruited in this study, including 64 children with IgAV and 387 with IgAV with nephritis (IgAVN), according to renal puncture results. Triglycerides, creatinine, urea, uric acid, cystatin C, immunoglobulin A, complement C3, and complement C4 were measured. Compared with the IgAV group, the children with IgAVN had higher triglycerides, creatinine, urea, uric acid and TG/CysC and lower cystatin C and complement C4 (p
Fields of Study & Subjects
Renal Diseases and Glomerulopathies
Vasculitis and related conditions
Complement system in diseases
Publication details
- Journal / source
- Journal of Clinical Biochemistry and Nutrition
- Volume
- 78
- Issue
- 3
- Pages
- 214–218
- Publication date
- 1 January 2026
- Language
- EN