Differential effects of follicle-stimulating hormone dosage on in vitro embryo production in high- and low-anti-Müllerian hormone Holstein heifers

Journal of Dairy Science 2026 Open access

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Authors: Jessica C.L. Motta, Rodrigo Vasconcellos Sala, Cameron B. Hayden, Daniela Pereira, Victor Antonio Absalón-Medina, Juan F. Moreno, Pablo J. Ross, A. García-Guerra
DOI: 10.3168/jds.2025-27587
Cited by: 1
References: 69

Abstract

Female cattle with low-anti-Müllerian hormone (AMH) have fewer antral follicles and reduced in vitro embryo production (IVEP) potential than high-AMH females. In addition, granulosa cells of low-AMH females have a diminished responsiveness to FSH, despite elevated circulating FSH concentrations. However, AMH phenotype is generally not considered when establishing FSH dosage for ovarian superstimulation. Thus, this study aimed to assess the effect of FSH dosage on IVEP outcomes in high- and low-AMH female cattle. Pregnant Holstein heifers (∼50 d of gestation) with high (>331 pg/mL; n = 31) and low (

Fields of Study & Subjects

Reproductive Physiology in Livestock Ovarian function and disorders Reproductive Biology and Fertility

Publication details

Journal / source
Journal of Dairy Science
Publisher
American Dairy Science Association
Volume
109
Issue
3
Pages
3093–3107
Publication date
15 January 2026
Language
EN