Milk metabolomic alterations correlated with intramammary infection in dairy cows: From healthy status to clinical mastitis

Journal of Dairy Science 2026 Open access

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Authors: A. Lisuzzo, M.C. Alterisio, S. Esposito, L. Laghi, A. Pesce, P. Ciaramella, F. Cecchini, G. Taio, M. Berlanda, M. Gianesella, J. Guccione, E. Fiore
DOI: 10.3168/jds.2025-27842
Cited by: 1
References: 65

Abstract

Mastitis is an udder inflammation and infection causing several economic losses in dairy cows. The milk metabolomic changes associated with clinical or subclinical mastitis have been investigated. However, little is known on milk metabolome associated with intramammary infection. The aim of this study was to investigate the quarter-milk metabolomic profile affected by intramammary infection, subclinical mastitis, and clinical mastitis in dairy cows. A total of 80 quarter-milk samples of multiparous Holstein-Friesian dairy cows were used in this cross-sectional design study. Samples were equally divided into 4 groups: healthy (H; no clinical signs of mastitis, SCC

Fields of Study & Subjects

Milk Quality and Mastitis in Dairy Cows Breastfeeding Practices and Influences Infant Nutrition and Health

Publication details

Journal / source
Journal of Dairy Science
Publisher
American Dairy Science Association
Volume
109
Issue
4
Pages
4423–4440
Publication date
21 February 2026
Language
EN