Multidisciplinary management of patients with hypertrophic cardiomyopathy

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Authors: K. V. Rudenko, P. A. Danchenko, M. I. Rzhanyi, O. O. Chyzhevska, A. O. Bei, O. M. Kovalyova
Cited by: 1
References: 42

Abstract

The article presents a review of literary and scientific sources from the MEDLINE database on PubMed, Web of Science, Scopus, and Google Scholar platforms, focusing on hypertrophic cardiomyopathy and its treatment aspects. In accordance with the recommendations of leading experts, a modern definition of hypertrophic cardiomyopathy is shown with a description of the classification of structural and functional cardiac abnormalities, associated symptoms, and generalized risk factors for sudden cardiac death in patients. A ranking of patients related to the left ventricular outflow tract obstruction and clinical manifestations is submitted. Based on international guidelines, the main principles for treating patients are given, depending on hemodynamic and clinical characteristics, including pharmacotherapy and invasive methods. Pathophysiological reasoning and clinical justification for prescribing drugs to correct complications are provided. The use of septal myectomy and alcohol septal ablation to correct morphological cardiac abnormalities and improve the clinical status of patients is outlined in a historical context. The results of one’s own experience in surgical treatment of patients with hypertrophic cardiomyopathy are presented.

Fields of Study & Subjects

Cardiomyopathy and Myosin Studies Pericarditis and Cardiac Tamponade Cardiovascular Function and Risk Factors

Publication details

Journal / source
Ukrainian Journal of Cardiology
Publisher
Chetverta Khvylia
Volume
33
Issue
1
Pages
75–85
Publication date
27 February 2026