Localized Outbreak of Macrolide-Resistant Pertussis in Infants, Japan, March–May 2025

Emerging infectious diseases 2026 Open access

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Authors: Takafumi Obara, Kyoko Kano, Takashi Yorifuji, Kohei Tsukahara, Naoki Yogo, Yuichiro Muto, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao, Katsuki Hirai
DOI: 10.3201/eid3201.250824
Cited by: 1
References: 7

Abstract

A localized pertussis outbreak involving 10 unvaccinated infants occurred in Kumamoto, Japan, during March-May 2025. Nine infants were admitted to the pediatric intensive care unit, 6 of whom received a confirmed diagnosis of macrolide-resistant Bordetella pertussis infection. This outbreak highlights the importance of booster vaccinations and resistance surveillance.

Fields of Study & Subjects

Bacterial Infections and Vaccines Pneumonia and Respiratory Infections Infectious Encephalopathies and Encephalitis

Publication details

Journal / source
Emerging infectious diseases
Publisher
Centers for Disease Control and Prevention (CDC)
Volume
32
Issue
1
Pages
158–161
Publication date
1 January 2026
Language
EN