Molecular Analysis of Emerging MT27 Macrolide-Resistant Bordetella pertussis, Kobe, Japan, 2025

Emerging infectious diseases 2026 Open access

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Authors: Shoko Komatsu, Noriko Nakanishi, Kousaku Matsubara, Yuui Inenaga, Masayuki Hori, Kiyo Shiotani, Rumi Morimoto, Chie Nantani, Yuki Muneta, Nobuya Kusunoki
DOI: 10.3201/eid3201.250890
Cited by: 1
References: 9

Abstract

We report the emergence and spread of multilocus variable-number tandem-repeat analysis type 27 (MT-27) macrolide-resistant Bordetella pertussis (MRBP) in Kobe, Japan, in 2025. Whole-genome sequencing revealed that MT27-MRBP did not originate from the widely circulating MT27 macrolide-sensitive B. pertussis in Japan but was closely related to MRBP in China.

Fields of Study & Subjects

Bacterial Infections and Vaccines Pneumonia and Respiratory Infections Epilepsy research and treatment

Publication details

Journal / source
Emerging infectious diseases
Publisher
Centers for Disease Control and Prevention (CDC)
Volume
32
Issue
1
Pages
150–153
Publication date
1 January 2026
Language
EN