Indeterminant Interferon-γ Release Assays in Refugee Children with Splenomegaly, Uganda, 2020–2023

Emerging infectious diseases 2026 Open access

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Authors: Christina R. Phares, Moses Mwesigwa, Sean R. Toney
DOI: 10.3201/eid3203.251200
Cited by: 0
References: 11

Abstract

We observed a novel association between splenomegaly and indeterminate interferon-γ release assays in refugee children 5-14 years of age in Uganda. Those demonstrating splenomegaly were 4 times more likely to have indeterminate results. Among refugee children 2-4 years of age, >10% had indeterminate results even without splenomegaly.

Fields of Study & Subjects

Tuberculosis Research and Epidemiology Immunodeficiency and Autoimmune Disorders Diagnosis and treatment of tuberculosis

Publication details

Journal / source
Emerging infectious diseases
Volume
32
Issue
3
Pages
457–459
Publication date
1 March 2026
Language
EN