Guillain-Barré Syndrome and Visual Impairment Associated with Emerging Oropouche Virus Lineage, Brazil, 2024

Emerging infectious diseases 2026 Open access

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Authors: Carlos Garcia Filho, Fernanda Martins Maia Carvalho, Antonio S. Lima Neto, Ana Maria Cabral Maia, Matheus Andrighetti Rossi, Milena Sales Pitombeira, Paula Camila Alves de Assis Pereira Matos, Tânia Mara Silva Coelho, Lauro Vieira Perdigão Neto, Lívia Mendes de Almeida, Felipe Gomes Naveca, Carla Santos de Oliveira
+5 more Fernanda de Bruycker-Nogueira, Ana María Bispo de Filippis, Kléber Giovanni Luz, Andre Ricardo Ribas Freitas, Luciano Pamplona de Góes Cavalcanti
DOI: 10.3201/eid3204.250617
Cited by: 1
References: 12

Abstract

We report a case of Guillain-Barré syndrome with visual impairment after confirmed Oropouche virus infection during the 2024 outbreak in Ceará, Brazil. Whole-genome sequencing revealed infection by a novel reassortant viral lineage (OROVBR_2025_2024), raising concern about the neurovirulence of this emerging orthobunyavirus strain.

Fields of Study & Subjects

Mosquito-borne diseases and control Peripheral Neuropathies and Disorders Multiple Sclerosis Research Studies

Publication details

Journal / source
Emerging infectious diseases
Publisher
Centers for Disease Control and Prevention (CDC)
Volume
32
Issue
4
Pages
644–648
Publication date
1 April 2026
Language
EN