Post-Traumatic Stress Disorder Modelled as a Complex Dynamic System

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Authors: Erik J. Giltay, Masanori Nagamine, Florentine H. S. van der Does, Eric H. G. J. M. Vermetten
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Abstract

The conventional view of posttraumatic stress disorder (PTSD) conceptualizes it as a latent disorder caused by exposure to a traumatic event. However, this perspective may fail to capture the condition’s marked heterogeneity, multifactorial origins, and complex nature. From a complex dynamic systems perspective, PTSD can be understood as a network of interrelated symptoms and contextual factors that evolve over time and mutually reinforce one another. Such interactions can create self-sustaining disorder states. Advances in digital health—such as continuous time-series data from wearable devices and real-time, personalized symptom monitoring—enable the identification of individual-specific patterns and triggers. Combining these data streams with computational psychiatry approaches can facilitate the early detection of destabilizing changes in the symptom network and provide timely, tailored feedback to patients and care teams. Applying a complex dynamic systems framework, in combination with digital tools and computational analysis, may promote self-management, support precision medicine, and ultimately improve outcomes and quality of life for individuals with PTSD.

Fields of Study & Subjects

Posttraumatic Stress Disorder Research Mental Health Research Topics Personality Disorders and Psychopathology

Publication details

Journal / source
NATO science for peace and security series. Sub-series E, Human and societal dynamics
Publication date
8 January 2026
Document type
Book chapter