Review of: "Effect of Clown Therapy on Symptoms and Emotions of Children with Neoplastic Disease: A Systematic Review with Meta-Analysis"

This systematic review and meta-analysis addresses a clinically relevant and underexplored supportivecare intervention in pediatric oncology by evaluating the effectiveness of clown therapy on symptom and emotional outcomes among children with neoplastic disease.The study demonstrates several methodological strengths, including protocol registration in PROSPERO, adherence to PRISMA guidelines, comprehensive database searching, application of the RoB 2 tool, use of random-effects metaanalysis, and structured evidence grading using GRADE.The inclusion of multiple psychosocial outcomes such as anxiety, pain, fatigue, fear, and mood provides a broad evaluation of patient-centered bene ts and highlights the importance of nonpharmacological supportive therapies in pediatric oncology.