12-O-Tetradecanoylphorbol-13-Acetate Inhibits TGF-β1-Induced Proliferation and Fibrosis in LX-2 Hepatic Stellate Cells by Regulating both YAP and AKT Activities

Biocell 2026 Open access

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Authors: Moo Hyun Kim, Yongdae Yoon, Chang Wan Kim, Jun-Won Lee, Bhupendra Regmi, Saher Fatima, Moon Young Kim, Soon Koo Baik, Pil Young Jung, Young Woo Eom
DOI: 10.32604/biocell.2026.076364
Cited by: 0

Abstract

Background: Although transforming growth factor-β (TGF-β) drives hepatic stellate cell activation and fibrogenesis, the mechanisms by which 12-O-tetradecanoylphorbol-13-acetate (TPA) modulates these processes in TGF-β1-act... | Find, read and cite all the research you need on Tech Science Press

Fields of Study & Subjects

Liver physiology and pathology TGF-β signaling in diseases Liver Disease Diagnosis and Treatment

Publication details

Journal / source
Biocell
Volume
50
Issue
6
Pages
1–10
Publication date
1 January 2026
Language
EN