GeRnika: An R Package for the Simulation, Visualization and Comparison of Tumor Phylogenies

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Authors: Aitor Sánchez-Ferrera, Maitena Tellaetxe-Abete, Borja Calvo Molinos
Cited by: 0
References: 31

Abstract

The development of methods to study intratumoral heterogeneity and tumor phylogenies is a highly active area of research. However, the advancement of these approaches often necessitates access to substantial amounts of data, which can be challenging and expensive to acquire. Moreover, the assessment of results requires tools for visualizing and comparing tumor phylogenies. In this paper, we introduce GeRnika, an R package designed to address these needs by enabling the simulation, visualization, and comparison of tumor evolution data. In summary, GeRnika provides researchers with a user-friendly tool that facilitates the analysis of their approaches aimed at studying tumor composition and evolutionary history.

Fields of Study & Subjects

Cancer Genomics and Diagnostics Single-cell and spatial transcriptomics Mathematical Biology Tumor Growth

Publication details

Journal / source
The R Journal
Volume
17
Issue
4
Pages
256–275
Publication date
11 February 2026
Language
EN