Synthesis and Bioactivity Study of Pyrazole and Benzoxazole Derivatives

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Authors: Sushama B. Dare, Rozina R. Shaikh, Hemantkumar N. Akolkar, Sadhana D. Mhaske, Sushama Jayawant Takate
Cited by: 0
References: 44

Abstract

A series of substituted pyrazolyl benzoxazoles (5a-f) was prepared using 3-formylchromones as precursors by cyclization of corresponding oximes. The structures of all the intermediates as well as pyrazolyl benzoxazoles were confirmed by analytical techniques like IR, PMR and mass spectrometry. All the synthesized compounds were screened for their α-amylase inhibitory, anti-oxidant and anti-inflammatory activities. Some of the compounds showed moderate to weak activities.

Fields of Study & Subjects

Synthesis and biological activity Synthesis of Organic Compounds Chemical synthesis and pharmacological studies

Publication details

Journal / source
International Journal of Scientific Research in Science Engineering and Technology
Volume
13
Issue
1
Pages
150–161
Publication date
15 January 2026