Advances in Laboratory Diagnosis of Lymph Node Metastasis in Papillary Thyroid Carcinoma: From Diagnostic Biomarkers to Multimodal Combined Applications
Abstract
Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the head and neck, with a generally slow disease progression and favorable prognosis in most patients. However, lymph node metastasis in a small subset of patients can reduce the five-year disease-free survival rate from 94.8% to 73.1%. Studies have confirmed that lymph node metastasis is a risk factor for poor prognosis. Therefore, this article analyzes and compares the diagnostic value of biomarkers, liquid biopsy, and combined detection techniques to evaluate their diagnostic efficacy in lymph node metastasis and prognosis, aiming to provide evidence-based support for optimizing clinical diagnostic pathways.
Fields of Study & Subjects
Thyroid Cancer Diagnosis and Treatment
Thyroid and Parathyroid Surgery
Head and Neck Cancer Studies
Publication details
- Journal / source
- Journal of Clinical Medicine Research
- Volume
- 6
- Issue
- 4
- Pages
- 650–650
- Publication date
- 29 January 2026
- Language
- EN