Exploration of Individualized Pharmacological Treatment and Prevention Strategies for Migraine

Migraine is a common primary headache disorder characterized by recurrent moderate to severe throbbing pain, often accompanied by nausea, vomiting, and photophobia. Its complex pathogenesis and significant individual differences lead to varying responses to conventional pharmacological treatments, making individualized treatment an important direction in clinical practice. This paper first reviews the pathological and physiological mechanisms of migraine, focusing on the roles of neurovascular regulation disorders, neurotransmitter imbalances, and genetic factors. Then, it explores individualized pharmacological treatment strategies from the perspectives of acute attack treatment and preventive treatment, aims to provide theoretical support and clinical reference for improving the efficacy of migraine treatment and reducing the recurrence rate.