Mortalidade por Sarcoma de Kaposi no Brasil e Regiões entre 1996 e 2023: Análise de Tendência Temporal

Introduction: Kaposi's sarcoma is a multicentric vascular neoplasm, clinically associated with acquired immunodeficiency syndrome (AIDS), which can lead to death. Objective: To verify the temporal trend of mortality from Kaposi's sarcoma in Brazilian regions between 1996 and 2023. Method: Ecological study of temporal trend analysis using secondary morbidity data available in the Department of Informatics of the National Health System (DATASUS/SIM), in the ICD-10 category (C46-Kaposi's sarcoma). The free software environment R and Prais-Winsten regression were used to analyze the time series. Results: A total of 2,226 deaths from Kaposi's sarcoma were reported during the 28 years analyzed, with the Southeast region showing the highest absolute frequency. Among the general population, there was an increasing trend in Kaposi's sarcoma mortality in Brazil, with an APC of 7%, particularly in the Northeast region, which had an APC of 32%, and the South region, with 37.4%. Among women, Brazil showed an increasing trend (7.9%), in addition to increases observed in the Northeast (127.6%) and South (78.5%) regions. Among men, the Northeast region showed a significant increase only from 2010 onwards, with a continuous increasing trend of 36.2%. Conclusion: The temporal analysis revealed an increasing trend in mortality from KS in Brazil and in the Northeast, South, and Central-West regions, with emphasis on the Northeast, especially among men. The North and Southeast regions remained stationary. The results emphasize the need for human immunodeficiency virus (HIV) diagnosis and treatment to prevent opportunistic diseases.