SUPERIOR MESENTERIC VEIN THROMBOSIS AND CYTOMEGALOVIRUS: A DIAGNOSTIC DILEMMA. A CASE REPORT AND REVIEW OF THE LITERATURE

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Authors: Vincenzo Davide Palumbo, Antonio Bruno, Giovanni Tomasello, Emanuele Sinagra, Giuseppe Damiano, Attilio Ignazio Lo Monte, Marcello Noto, Enzo Maria Acruleo
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Abstract

Superior mesenteric vein thrombosis (SMVT) is a rare condition, usually caused by infections, intra-abdominal inflammatory diseases. portal hypertension, hypercoagulable states, or contraceptive therapy. Due to its vague symptomatology, SMVT is often diagnosed only after an abdominal contrast-enhanced computed tomography (CT) scan. In this article, we present a case of SMVT in a patient with a history of contraceptive drug use and a recent cytomegalovirus infection.A 36-year-old female was admitted to our department with the clinical symptoms of an acute appendicitis. The patient was a smoker and had been using hormonal contraceptives for over a year. Surgery was deemed the best course of action. Before the operation, blood tests showed a mild lymphocytosis and altered liver enzyme levels, while coagulation values were normal. A contrast-enhanced CT scan revealed a complete superior mesenteric vein thrombosis without signs of bowel ischemia. Anticoagulants were immediately administered. A thrombophilia panel did not highlight any noteworthy elements. Cytomegalovirus (CMV) tests resulted positive.Since CMV is a rare, but potentially significant cause or precipitating factor for thrombosis in immunocompetent hosts, all patients with an unexplained fever and seemingly spontaneous thrombosis should be screened for CMV infection.

Fields of Study & Subjects

Aortic Thrombus and Embolism Dermatological and COVID-19 studies Vascular Malformations and Hemangiomas

Publication details

Journal / source
EuroMediterranean Biomedical Journal
Publisher
PAGEPress Publications
Volume
9
Publication date
12 January 2026
Language
EN